Nitrofurantoin 100mg modified-release

• Do not use if you:

  • Are allergic to nitrofurantoin or any other ingredients in Macrobid.
  • Have severe kidney disease, as the medication may not reach effective levels in the urine.
  • Are in the last trimester of pregnancy unless specifically advised by a doctor.

• Consult your healthcare provider before use if you:

  • Have liver disease or a history of liver problems.
  • Have anemia, diabetes, or electrolyte imbalances.
  • Are breastfeeding, as small amounts of nitrofurantoin may pass into breast milk.

• Potential for interactions:

  • Inform your doctor of all medications you are taking, as Macrobid can interact with antacids, gout medications (e.g., probenecid), and other antibiotics.

• Driving and operating machinery:

  • Nitrofurantoin may cause dizziness or drowsiness in some patients. Avoid driving if you feel affected.

• Complete the course:

  • Even if symptoms improve, complete the full course of Macrobid to ensure the infection is fully treated and prevent antibiotic resistance.

• How to take:

  • Swallow the capsule whole with water.
  • Take with food or milk to improve absorption and reduce the likelihood of stomach upset.

• Dosage:

  • The usual adult dose is 100mg twice daily for 3-7 days, depending on the infection and as prescribed by your doctor.

• Missed dose:

  • If you miss a dose, take it as soon as you remember. If it’s close to the next dose, skip the missed dose and resume your regular schedule. Do not double up doses.

• Storage:

  • Store Macrobid capsules at room temperature, away from moisture, heat, and direct sunlight.

Active Ingredient:

• Nitrofurantoin (100mg): An antibiotic that targets and kills bacteria in the urinary tract.

Other Ingredients:

• Lactose
• Gelatin
• Magnesium stearate
• Other capsule stabilizers

These inactive ingredients help form the capsule and deliver the active compound effectively.

Common Side Effects:

1. Nausea or vomiting: Taking Macrobid with food can help minimize these effects.
2. Diarrhea: A temporary effect that usually resolves after completing the course.
3. Headache: A mild headache may occur in some patients.

Less Common Side Effects:

1. Loss of appetite: Some users report reduced appetite during treatment.
2. Dizziness or drowsiness: Rarely, patients may feel lightheaded or fatigued.

Rare Side Effects:

1. Allergic reaction: Symptoms include rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if these occur.
2. Lung problems: In rare cases, nitrofurantoin can cause lung inflammation. Symptoms include shortness of breath, coughing, or chest pain.
3. Liver problems: Watch for symptoms like yellowing of the skin or eyes (jaundice) and seek medical advice if they occur.

1. How does Macrobid work?
   Macrobid contains nitrofurantoin, which damages bacterial DNA, preventing bacteria from growing and spreading. This clears up the infection in the urinary tract.

2. How long does Macrobid take to work?
   Symptom relief often begins within 1-2 days, but the full course should be completed to prevent the infection from returning or bacteria from becoming resistant.

3. How often should I take Macrobid?
   Macrobid is usually taken twice daily (every 12 hours), with food or milk to reduce stomach upset and improve absorption.

4. Can Macrobid treat all types of UTIs?
   Macrobid is effective for uncomplicated lower UTIs (e.g., cystitis). It is not suitable for severe kidney infections (e.g., pyelonephritis) or systemic infections.

5. Is Macrobid safe during pregnancy?
   Macrobid is generally considered safe for use during pregnancy but should be avoided in the last trimester unless directed by a doctor, as it may affect the baby’s red blood cells.