Nitrofurantoin 100mg modified-release

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Macrobid contains nitrofurantoin, an antibiotic used to treat urinary tract infections (UTIs), including cystitis. The modified-release formulation provides a steady release of medication over time, ensuring effective treatment with twice-daily dosing. Nitrofurantoin works by targeting and killing bacteria responsible for infections in the urinary tract, offering fast relief from symptoms such as pain, burning during urination, and frequent urination.

Available Strength 100mg

Available Quantity 6

Nitrofurantoin is an antibiotic used to treat uncomplicated urinary tract infections (UTIs) such as cystitis in women.

Short course of capsules
Treats uncomplicated UTIs
Reviewed by UK-registered clinicians
Discreet, tracked delivery

What is Nitrofurantoin 100mg modified-release?

Targets urinary tract infections: Effective against most bacteria causing UTIs, including E. coli.
Modified-release capsules: Provide sustained action for consistent antibiotic coverage.
Twice-daily dosing: Convenient regimen for patient compliance.
Rapid symptom relief: Reduces UTI symptoms within a few days of starting treatment.

Macrobid is typically prescribed for short-term use, usually over 3-7 days, depending on the severity of the infection.

How to use Nitrofurantoin 100mg modified-release

How to take:

-> Swallow the capsule whole with water.

-> Take with food or milk to improve absorption and reduce the likelihood of stomach upset.

Dosage:

-> The usual adult dose is 100mg twice daily for 3-7 days, depending on the infection and as prescribed by your doctor.

Missed dose:

-> If you miss a dose, take it as soon as you remember. If it’s close to the next dose, skip the missed dose and resume your regular schedule. Do not double up doses.
Storage:

-> Store Macrobid capsules at room temperature, away from moisture, heat, and direct sunlight.

Possible side effects

Common Side Effects:

-> Nausea or vomiting: Taking Macrobid with food can help minimize these effects.

-> Diarrhea: A temporary effect that usually resolves after completing the course.

-> Headache: A mild headache may occur in some patients.

Less Common Side Effects:

-> Loss of appetite: Some users report reduced appetite during treatment.

-> Dizziness or drowsiness: Rarely, patients may feel lightheaded or fatigued.

Rare Side Effects:

-> Allergic reaction: Symptoms include rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if these occur.

-> Lung problems: In rare cases, nitrofurantoin can cause lung inflammation. Symptoms include shortness of breath, coughing, or chest pain.

-> Liver problems: Watch for symptoms like yellowing of the skin or eyes (jaundice) and seek medical advice if they occur.

Warnings and precautions

Even if symptoms improve, complete the full course of Macrobid to ensure the infection is fully treated and prevent antibiotic resistance.Do not use if you:

-> Are allergic to nitrofurantoin or any other ingredients in Macrobid.

-> Have severe kidney disease, as the medication may not reach effective levels in the urine.

-> Are in the last trimester of pregnancy unless specifically advised by a doctor.

Consult your healthcare provider before use if you:

-> Have liver disease or a history of liver problems.

-> Have anemia, diabetes, or electrolyte imbalances.

-> Are breastfeeding, as small amounts of nitrofurantoin may pass into breast milk.

Potential for interactions:

-> Inform your doctor of all medications you are taking, as Macrobid can interact with antacids, gout medications (e.g., probenecid), and other antibiotics.
Driving and operating machinery:

-> Nitrofurantoin may cause dizziness or drowsiness in some patients. Avoid driving if you feel affected.

Complete the course:

-> Even if symptoms improve, complete the full course of Macrobid to ensure the infection is fully treated and prevent antibiotic resistance.

What are the ingredients in Nitrofurantoin 100mg modified-release?

Active Ingredient:

Nitrofurantoin (100mg): An antibiotic that targets and kills bacteria in the urinary tract.

Other Ingredients:

Lactose
Gelatin
Magnesium stearate
Other capsule stabilizers

These inactive ingredients help form the capsule and deliver the active compound effectively.

Frequently asked questions

Everything you need to know about Nitrofurantoin 100mg modified-release before you start.

How does Macrobid work?
Macrobid contains nitrofurantoin, which damages bacterial DNA, preventing bacteria from growing and spreading. This clears up the infection in the urinary tract.
How long does Macrobid take to work?
Symptom relief often begins within 1-2 days, but the full course should be completed to prevent the infection from returning or bacteria from becoming resistant.
How often should I take Macrobid?
Macrobid is usually taken twice daily (every 12 hours), with food or milk to reduce stomach upset and improve absorption.
Can Macrobid treat all types of UTIs?
Macrobid is effective for uncomplicated lower UTIs (e.g., cystitis). It is not suitable for severe kidney infections (e.g., pyelonephritis) or systemic infections.
Is Macrobid safe during pregnancy?
Macrobid is generally considered safe for use during pregnancy but should be avoided in the last trimester unless directed by a doctor, as it may affect the baby’s red blood cells.

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Regulated by the GPhC

Regulated by the CQC

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ICO Certified

Regulated by the MHRA

How it works

Throughout your treatment, the SwiftDoctor clinical team is available to support you, answer questions, and review your progress.

Step 1

Complete your health questionnaire online in less than five minutes

Takes less than five minutes. Answer a few straightforward questions about your health history, lifestyle, and goals — all from the comfort of your home, with no GP appointment needed. Add your desired medication to your basket and make payment.
Step 2

A UK-registered clinician reviews your responses

A UK-registered clinician personally evaluates your submission to ensure Mounjaro is safe and appropriate for you. Your health is never treated as a formality.
Step 3

If eligible, your prescription is issued

If you meet the clinical criteria, your prescription is approved and prepared without delay. No waiting rooms. No repeat visits. Just a clear, straightforward process.
Step 4

Your medication is dispatched in discreet, temperature-controlled packaging directly to your address

Your medication is dispatched in plain, temperature-controlled packaging — protecting both its integrity and your privacy. Straight to your address, on your schedule.

Meet our clinical team

Dr S. Bano
Dr Bano is a co-founder of SwiftDoctor. She is an experienced General Practitioner with a special interest in obesity management, medical education, and digital health. She qualified as a doctor from the University of Nottingham in 2011 and has since built a diverse and impactful career in both clinical and educational settings.
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Nasir Ali
Mr Nasir Ali is a co-founder and the Superintendent Pharmacist at SwiftDoctor. He is a highly experienced Advanced Clinical Practitioner. With extensive experience in primary care, he has worked across GP surgeries and digital health clinics, bringing a deep understanding of both face-to-face and virtual models of care.
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Jane Eastwood
I am a Registered Nurse with 23 years’ experience – I have worked extensively in New Zealand and in the UK and I currently work as an Advanced Clinical Practitioner in the General Practice setting and I have special interests in menopause, diabetes, general practice and the older adult.
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