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Nitrofurantoin 100mg modified-release
Nitrofurantoin 100mg modified-release
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Macrobid contains nitrofurantoin, an antibiotic used to treat urinary tract infections (UTIs), including cystitis. The modified-release formulation provides a steady release of medication over time, ensuring effective treatment with twice-daily dosing. Nitrofurantoin works by targeting and killing bacteria responsible for infections in the urinary tract, offering fast relief from symptoms such as pain, burning during urination, and frequent urination.
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Description
Macrobid contains nitrofurantoin, an antibiotic used to treat urinary tract infections (UTIs), including cystitis. The modified-release formulation provides a steady release of medication over time, ensuring effective treatment with twice-daily dosing. Nitrofurantoin works by targeting and killing bacteria responsible for infections in the urinary tract, offering fast relief from symptoms such as pain, burning during urination, and frequent urination.
- Targets urinary tract infections: Effective against most bacteria causing UTIs, including E. coli.
- Modified-release capsules: Provide sustained action for consistent antibiotic coverage.
- Twice-daily dosing: Convenient regimen for patient compliance.
- Rapid symptom relief: Reduces UTI symptoms within a few days of starting treatment.
Macrobid is typically prescribed for short-term use, usually over 3-7 days, depending on the severity of the infection.
Warnings
- Even if symptoms improve, complete the full course of Macrobid to ensure the infection is fully treated and prevent antibiotic resistance.Do not use if you:
-> Are allergic to nitrofurantoin or any other ingredients in Macrobid.
-> Have severe kidney disease, as the medication may not reach effective levels in the urine.
-> Are in the last trimester of pregnancy unless specifically advised by a doctor.
- Consult your healthcare provider before use if you:
-> Have liver disease or a history of liver problems.
-> Have anemia, diabetes, or electrolyte imbalances.
-> Are breastfeeding, as small amounts of nitrofurantoin may pass into breast milk.
- Potential for interactions:
-> Inform your doctor of all medications you are taking, as Macrobid can interact with antacids, gout medications (e.g., probenecid), and other antibiotics.
- Driving and operating machinery:
-> Nitrofurantoin may cause dizziness or drowsiness in some patients. Avoid driving if you feel affected.
- Complete the course:
-> Even if symptoms improve, complete the full course of Macrobid to ensure the infection is fully treated and prevent antibiotic resistance.
Directions
- How to take:
-> Swallow the capsule whole with water.
-> Take with food or milk to improve absorption and reduce the likelihood of stomach upset.
- Dosage:
-> The usual adult dose is 100mg twice daily for 3-7 days, depending on the infection and as prescribed by your doctor.
- Missed dose:
-> If you miss a dose, take it as soon as you remember. If it’s close to the next dose, skip the missed dose and resume your regular schedule. Do not double up doses.
- Storage:
-> Store Macrobid capsules at room temperature, away from moisture, heat, and direct sunlight.
Ingredients
Active Ingredient:
- Nitrofurantoin (100mg): An antibiotic that targets and kills bacteria in the urinary tract.
Other Ingredients:
- Lactose
- Gelatin
- Magnesium stearate
- Other capsule stabilizers
These inactive ingredients help form the capsule and deliver the active compound effectively.
Side Effects
Common Side Effects:
-> Nausea or vomiting: Taking Macrobid with food can help minimize these effects.
-> Diarrhea: A temporary effect that usually resolves after completing the course.
-> Headache: A mild headache may occur in some patients.
Less Common Side Effects:
-> Loss of appetite: Some users report reduced appetite during treatment.
-> Dizziness or drowsiness: Rarely, patients may feel lightheaded or fatigued.
Rare Side Effects:
-> Allergic reaction: Symptoms include rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if these occur.
-> Lung problems: In rare cases, nitrofurantoin can cause lung inflammation. Symptoms include shortness of breath, coughing, or chest pain.
-> Liver problems: Watch for symptoms like yellowing of the skin or eyes (jaundice) and seek medical advice if they occur.
FAQs
- How does Macrobid work?
Macrobid contains nitrofurantoin, which damages bacterial DNA, preventing bacteria from growing and spreading. This clears up the infection in the urinary tract.
- How long does Macrobid take to work?
Symptom relief often begins within 1-2 days, but the full course should be completed to prevent the infection from returning or bacteria from becoming resistant.
- How often should I take Macrobid?
Macrobid is usually taken twice daily (every 12 hours), with food or milk to reduce stomach upset and improve absorption.
- Can Macrobid treat all types of UTIs?
Macrobid is effective for uncomplicated lower UTIs (e.g., cystitis). It is not suitable for severe kidney infections (e.g., pyelonephritis) or systemic infections.
- Is Macrobid safe during pregnancy?
Macrobid is generally considered safe for use during pregnancy but should be avoided in the last trimester unless directed by a doctor, as it may affect the baby’s red blood cells.