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Naproxen Tablets

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Naproxen is a prescription-only anti-inflammatory painkiller (NSAID) used to relieve pain, swelling and stiffness. It is used for conditions such as back pain, sprains and strains, osteoarthritis, rheumatoid arthritis, gout and period pain.

Naproxen tablets are available in 250mg and 500mg strengths, in packs of 28 or 56. Complete a short online consultation and our UK-registered clinicians will check whether naproxen is suitable for you before anything is prescribed.

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Naproxen is an anti-inflammatory painkiller (NSAID) that relieves pain, swelling and stiffness, including back and joint pain.

  • Anti-inflammatory tablets
  • Eases pain, swelling and stiffness
  • Reviewed by UK-registered clinicians
  • Discreet, tracked delivery

What is Naproxen?

What is Naproxen?

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and inflammation. It is used to treat conditions such as osteoarthritis, rheumatoid arthritis, gout, period pain, and joint and muscle problems, including back pain, sprains and strains. You can buy some types of naproxen from a pharmacy, but others, including these tablets, are only available on prescription.

How Does Naproxen Work?

Naproxen works by blocking the action of chemicals in the body called cyclo-oxygenase (COX) enzymes. These enzymes help to produce other chemicals called prostaglandins, a type of chemical that causes pain and inflammation when produced at damaged or injured areas of the body. By blocking these enzymes, naproxen reduces the amount of prostaglandins made, which eases pain, swelling and stiffness.

How to use Naproxen

Follow the instructions given by your clinician and the patient information leaflet.

  • Take naproxen with or just after food, to help protect your stomach.
  • Naproxen is typically taken two or three times per day. The dose will vary depending on the condition being treated.
  • If you are taking Naproxen tablets, do not crush or chew them. Swallow them whole with water.
  • When taking the suspension, shake the liquid well to mix it evenly before use.
  • The recommended dose for rheumatoid arthritis is 500mg-1g a day, to be taken in two doses at twelve hourly intervals.
  • To treat gout, you should take an initial dose of 750mg, followed by 250mg every eight hours until the attack has passed.
  • For painful periods, or muscle and bone disorders, take an initial dose of 500mg, followed by 250mg every 6-8 hours. After the first day, you can take up to 1250mg per day.
  • Use the lowest dose that works for the shortest time you need it, to reduce the risk of side effects.
Possible side effects

Common side effects can include:

  • Bleeding from the stomach or intestines
  • Hypertension
  • Liver damage
  • Constipation or diarrhoea
  • Nausea or vomiting
  • Headaches, dizziness or feeling tired
  • Asthma attacks
  • Bloating or stomach pain
  • Ringing in the ears (tinnitus)

If you suffer any serious or prolonged side effects, contact your healthcare provider. Stop taking naproxen and get medical help straight away if you have signs of bleeding in your stomach (such as black, tar-like poo or vomiting blood), shortness of breath, swelling in your ankles or legs, blood in your pee, or an allergic reaction such as a swollen throat or tongue or difficulty breathing.

Warnings and precautions
  • Always inform your doctor of any underlying medical or allergic conditions you experience.
  • Inform your doctor of any prescription medication you are currently using, especially blood thinners such as warfarin, steroids, antidepressants, diuretics, blood pressure medicines or methotrexate.
  • Inform your doctor of your pregnancy or breastfeeding status before taking Naproxen. Naproxen is usually avoided during pregnancy and while breastfeeding.
  • Do not take Naproxen if you have liver, kidney or heart conditions without your doctor's approval.
  • Do not take naproxen if you have had an allergic reaction to naproxen, ibuprofen, aspirin or another NSAID, or if you have a stomach ulcer or have had one before.
  • Do not take naproxen at the same time as other NSAIDs, such as ibuprofen or aspirin, as this increases the risk of stomach ulcers.
  • Speak to your clinician first if you have asthma, a blood clotting problem, Crohn's disease or ulcerative colitis, or have had a stroke.
What are the ingredients in Naproxen?

The active ingredient in each tablet is naproxen, either 250mg or 500mg depending on the strength.

The inactive ingredients can vary between manufacturers, so check the patient information leaflet supplied with your tablets. They may include Maize starch, Purified talc, Methacrylic acid-ethylacrylate copolymer, Lactose, Xanthan gum, Titanium dioxide, Magnesium Stearate, Crospovidone, Propylene glycol, Potassium sorbate, Sodium hydroxide, Triethyl citrate, Sodium citrate, Hydroxypropyl cellulose, and Beeswax. These tablets contain lactose, so speak to your clinician first if you have an intolerance to some sugars.

Frequently asked questions

Everything you need to know about Naproxen before you start.

1. What is the difference between Naproxen 250mg and 500mg?

Both strengths contain the same medicine, so the difference is the amount of naproxen in each tablet. Having both strengths lets your clinician match the dose to your condition, as shown in the dosing guide above. SwiftDoctor offers naproxen 250mg and 500mg tablets in packs of 28 or 56.

2. How long does naproxen take to work?

Naproxen can start to ease pain within about an hour, but it might take up to 3 days to work properly if you take it regularly twice a day. It does not work for some types of pain, such as nerve pain.

3. Can I drink alcohol while taking naproxen?

Yes, but try to limit how much you drink. Alcohol can irritate your stomach and increase the risk of side effects such as stomach ulcers or bleeding.

4. Will I need a medicine to protect my stomach?

If you are at higher risk of a stomach ulcer, for example because you are older or need naproxen for a long time, your clinician may recommend a second medicine, such as omeprazole, to protect your stomach.

5. Is Naproxen suitable for children?

Naproxen is mainly used in adults. Some types can be prescribed for children from 5 years old, usually for juvenile arthritis, but only by a doctor.

6. What if I miss a dose?

Take it as soon as you remember, but skip if it's close to the next dose. Do not double up.

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How it works

Throughout your treatment, the SwiftDoctor clinical team is available to support you, answer questions, and review your progress.

  • Step 1

    Complete your health questionnaire online in less than five minutes

    Takes less than five minutes. Answer a few straightforward questions about your health history, lifestyle, and goals — all from the comfort of your home, with no GP appointment needed. Add your desired medication to your basket and make payment.

  • Step 2

    A UK-registered clinician reviews your responses

    A UK-registered clinician personally evaluates your submission to ensure Mounjaro is safe and appropriate for you. Your health is never treated as a formality.

  • Step 3

    If eligible, your prescription is issued

    If you meet the clinical criteria, your prescription is approved and prepared without delay. No waiting rooms. No repeat visits. Just a clear, straightforward process.

  • Step 4

    Your medication is dispatched in discreet, temperature-controlled packaging directly to your address

    Your medication is dispatched in plain, temperature-controlled packaging — protecting both its integrity and your privacy. Straight to your address, on your schedule.

  • Dr S. Bano

    Dr Bano is a co-founder of SwiftDoctor. She is an experienced General Practitioner with a special interest in obesity management, medical education, and digital health. She qualified as a doctor from the University of Nottingham in 2011 and has since built a diverse and impactful career in both clinical and educational settings.

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  • Nasir Ali

    Mr Nasir Ali is a co-founder and the Superintendent Pharmacist at SwiftDoctor. He is a highly experienced Advanced Clinical Practitioner. With extensive experience in primary care, he has worked across GP surgeries and digital health clinics, bringing a deep understanding of both face-to-face and virtual models of care.

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  • Jane Eastwood

    I am a Registered Nurse with 23 years’ experience – I have worked extensively in New Zealand and in the UK and I currently work as an Advanced Clinical Practitioner in the General Practice setting and I have special interests in menopause, diabetes, general practice and the older adult.

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