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Trimethoprim

Trimethoprim

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Trimethoprim is an antibiotic used to treat bladder cystitis and urinary tract infections (UTIs). The drug helps relieve the burning pain, itching, and discomfort that comes with UTIs. Trimethoprim helps women, who are more prone to UTIs than men, to manage their symptoms. It is advisable to maintain cleanliness and sexual hygiene to prevent UTIs from recurring. 

 

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Description

What Is Trimethoprim?

Trimethoprim is an antibiotic used to treat bladder cystitis and urinary tract infections (UTIs). The drug helps relieve the burning pain, itching, and discomfort that comes with UTIs. Trimethoprim helps women, who are more prone to UTIs than men, to manage their symptoms. It is advisable to maintain cleanliness and sexual hygiene to prevent UTIs from recurring. Taking a three-day course of Trimethoprim will clear most bladder and urinary tract infections. Trimethoprim is recommended where nitrofurantoin is unsuitable for treating cystitis due to side effects.

How Does Trimethoprim Work?

Most cystitis originates from the gut, known as E.coli. Trimethoprim does not kill E.coli. It works by stopping bacterial DNA synthesis, meaning that the bacteria cannot replicate. This allows your immune system to destroy the infecting bacteria until they get eradicated and your infection gets resolved. The bacteria gets out of the body through the urinary tract when urinating. Symptoms including high temperatures and pain improve with 24-48 hours of taking Trimethoprim. However, you should complete the entire course to avoid bacterial resistance to the drug.

Warnings

Avoid Trimethoprim for treating UTI infections if the following apply to you:

  • You are allergic to Trimethoprim.
  • You have liver or kidney problems.
  • You have folate deficiency.
  • You have hyperkaliemia.
  • You have galactose intolerance.
  • You are pregnant or breastfeeding.

Directions

Take following the guidance of your doctor or after reading the instructions.

  • Trimethoprim is an oral medicine suitable for women over 18 years.
  • Take Trimethoprim 200mg tablets twice daily, one dosage every 12 hours until the prescribed course is complete.
  • Swallow the capsule with a glass of water.
  • The tablets are not affected by food or alcohol.

Ingredients

Your treatment contains 200mg of Trimethoprim per tablet.

Each tablet also contains the inactive ingredients anhydrous lactose, colloidal silicon dioxide, magnesium stearate, sodium lauryl sulfate, sodium starch glycolate, and stearic acid.

Side Effects

Like all medicines, some patients experience unpleasant side effects when taking Trimethoprim. Even though the drug is generally well-tolerated, consult your GP if you experience:

  • Diarrhoea
  • Nausea and vomiting
  • Stomach upset
  • Loss of appetite
  • Changes in taste
  • Headache

If you experience severe side effects, contact your healthcare provider.

 

FAQs

1. How long does it take for Trimethoprim to work?

Most people see improvement within a few days, but it’s important to complete the entire course as prescribed by your doctor​/

2. Can I take Trimethoprim if I am pregnant?

Trimethoprim is not generally recommended during the first trimester of pregnancy due to its impact on folic acid levels. Your doctor may prescribe folic acid supplements if needed​.

3. What are common side effects?

Common side effects include nausea, headache, itching, and diarrhea. Serious side effects, like severe allergic reactions, are rare​.

4. Can Trimethoprim affect contraception?

It may reduce the effectiveness of oral contraceptives if you experience vomiting or diarrhea for more than 24 hours​.

5. How should I take Trimethoprim?

Take the tablets twice daily, ideally spaced 12 hours apart, and continue the full course even if symptoms improve. Trimethoprim can be taken with or without food​

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